CDK15

Across TCGA patient cohorts, CDK15 protein abundance is significantly associated with the protein abundance of many other proteins, with 12 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CDK15-associated proteins across cancer lineages are ZNF146_S207, SRSF5_S231, and TOMM5. Each is linked with CDK15 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDK15-to-partner and partner-to-CDK15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDK15 versus ZNF146_S207 in GBM, with a Pearson correlation of 0.43.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK15→partner) and Y-score (partner→CDK15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF146_S207 →	+0.508	+0.545	.008	.002	1	1
GBM	SRSF5_S231 →	+1.169	+0.642	.003	.008	1	1
GBM	TOMM5 →	+0.499	+0.545	.008	.002	1	1
GBM	UBE2E2_S19 →	+0.698	+0.544	.009	.002	1	1
GBM	UBR2_S734 →	-0.589	-0.871	.003	.008	1	1
GBM	BICD2_S574 →	+0.618	+0.545	.008	.002	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

CDK15 vs ZNF146_S207 — GBM

Explore this scatter interactively →