CDK15

Across TCGA cell cohorts, CDK15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,286 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CDK15-associated GO terms across cancer lineages are Maintenance of protein localization in organelle, Dentinogenesis, and Maintenance of protein location in cell. Each is linked with CDK15 in more than 13 cancer types. Because this analysis shows association rather than direction, both CDK15-to-partner and partner-to-CDK15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein localization in organelle grouped by CDK15-low versus CDK15-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDK15→partner) and Y-score (partner→CDK15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Maintenance of protein localization in organelle →	+0.135	+1.895	<.001	.001	3	14
BONE	Dentinogenesis →	+1.880	+1.801	<.001	<.001	3	13
LIVER	Maintenance of protein location in cell →	+0.146	+1.895	<.001	.001	3	13
LIVER	Maintenance of protein location →	+0.145	+1.895	<.001	.001	3	13
BREAST	Regulation of protein maturation →	+0.163	+1.026	<.001	.004	3	13
BREAST	Actin filament severing →	+0.166	+1.030	<.001	.006	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,286 associations by consensus.

Maintenance of protein localization in organelle by CDK15 expression — LIVER

Explore this box plot interactively →