CDH3

Across TCGA patient cohorts, CDH3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,122 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDH3-associated proteins across cancer lineages are UBASH3B, BCL10, and UPP1. Each is linked with CDH3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CDH3-to-partner and partner-to-CDH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDH3 versus UBASH3B in BRCA, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH3→partner) and Y-score (partner→CDH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBASH3B →	+0.528	+1.717	<.001	<.001	3	6
PDAC	BCL10 →	+0.383	+0.703	<.001	.005	3	6
HNSC	UPP1 →	+0.644	+0.865	<.001	<.001	3	5
BRCA	RBMS2 →	+0.381	+1.440	.001	.005	3	5
HNSC	MT2A →	+1.097	+1.120	<.001	<.001	3	5
HNSC	MYEF2_S17 →	-0.928	-0.900	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,122 associations by consensus.

CDH3 vs UBASH3B — BRCA

Explore this scatter interactively →