CDH16

Across TCGA cell cohorts, CDH16 mutation is significantly associated with the RNA expression of many other genes, with 565 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDH16-associated genes across cancer lineages are ABHD17B, OR9G1, and HSF2. Each is linked with CDH16 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDH16-to-partner and partner-to-CDH16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABHD17B grouped by CDH16-low versus CDH16-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDH16→partner) and Y-score (partner→CDH16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ABHD17B →	+0.938	+3.260	.007	.005	3	2
BLOOD_Leukemia	OR9G1 →	+0.120	+2.704	<.001	.005	3	2
BLOOD_Leukemia	HSF2 →	+0.597	+3.199	.006	.007	3	2
BLOOD_Leukemia	HSD17B6 →	+1.003	+3.199	<.001	.007	3	2
BLOOD_Leukemia	FAM240A →	+0.010	+2.979	.001	.007	3	2
LARGE_INTESTINE	PDP2 →	+0.675	+3.212	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 565 associations by consensus.

ABHD17B by CDH16 expression — BLOOD_Leukemia

Explore this box plot interactively →