CDCA7

Across TCGA cell cohorts, CDCA7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,782 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CDCA7-associated GO terms across cancer lineages are DNA replication initiation, Cell cycle DNA replication initiation, and Nuclear cell cycle DNA replication initiation. Each is linked with CDCA7 in more than 18 cancer types. Because this analysis shows association rather than direction, both CDCA7-to-partner and partner-to-CDCA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by CDCA7-low versus CDCA7-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA7→partner) and Y-score (partner→CDCA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication initiation →	+0.195	+2.778	<.001	.001	3	19
BONE	Cell cycle DNA replication initiation →	+0.212	+1.778	<.001	.003	3	18
BONE	Nuclear cell cycle DNA replication initiation →	+0.212	+1.778	<.001	.003	3	18
BONE	Mitotic DNA replication initiation →	+0.212	+1.778	<.001	.003	3	18
BONE	Resolution of DNA recombination intermediates →	+0.208	+2.393	.001	.001	3	18
BONE	Nuclear DNA replication →	+0.218	+2.409	<.001	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,782 associations by consensus.

DNA replication initiation by CDCA7 expression — BLOOD_Myeloma

Explore this box plot interactively →