CDCA7

Across TCGA pan-cancer cohorts, CDCA7 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated CDCA7 data layer compared with 4 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CDCA7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CDCA7 expression acts as an unfavorable survival marker, although some lineages such as UCS and STAD show a favorable association.

ACC, UVM, and KIRC are the cancer types where CDCA7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.180	0.684	<.001	151	view →
UVM	DFS	Median	All	0.396	0.774	<.001	136	view →
KIRC	DFS	Tertile	All	0.485	0.710	<.001	134	view →
MESO	OS	Median	All	0.246	0.535	<.001	126	view →
KIRP	DFS	Quartile	All	0.718	0.921	<.001	80	view →
BRCA	OS	Median	II,III,IV	0.500	0.632	<.001	53	view →
LGG	OS	Median	All	0.742	0.876	<.001	49	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
LIHC	OS	Tertile	All	0.700	0.829	.005	34	view →
STAD	OS	Quartile	II,III,IV	0.770	0.612	.013	27	view →
GBM	DFS	Quartile	All	0.532	0.194	.002	15	view →
OV	OS	Median	IV	0.743	0.507	.010	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

CDCA7–ACC (DFS)

Open the ACC breakdown →