CDCA7

Across TCGA pan-cancer cohorts, CDCA7 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of CDCA7’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CDCA7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CDCA7 is over-expressed in tumor, although a few such as KICH and PRAD show the opposite, repressed pattern.

BLCA, KIRP, and COAD are the cancer types where CDCA7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDCA7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	+2.385	<.001	11	view →
KIRP	All	III,IV	+1.945	<.001	11	view →
COAD	Female	II,III,IV	+1.752	<.001	11	view →
KIRC	Male	IV	+1.172	<.001	11	view →
LUAD	Male	II,III,IV	+2.673	<.001	9	view →
LUSC	Male	II,III,IV	+3.073	<.001	8	view →
STAD	All	III,IV	+2.481	<.001	8	view →
HNSC	Male	All	+1.365	<.001	8	view →
LIHC	All	II,III,IV	+0.982	<.001	7	view →
UCEC	All	II,III,IV	+2.350	<.001	6	view →
READ	Female	All	+1.823	<.001	5	view →
BRCA	All	II,III,IV	+0.409	.024	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

CDCA7–BLCA

Open the BLCA breakdown →