CDC42-IT1

Across TCGA patient cohorts, CDC42-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,090 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CDC42-IT1-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Mitochondrial membrane organization, and Positive regulation of double-strand break repair. Each is linked with CDC42-IT1 in more than 29 cancer types. Because this analysis shows association rather than direction, both CDC42-IT1-to-partner and partner-to-CDC42-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by CDC42-IT1-low versus CDC42-IT1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC42-IT1→partner) and Y-score (partner→CDC42-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.054	+0.477	<.001	<.001	3	30
STAD	Mitochondrial membrane organization →	+0.056	+0.502	<.001	<.001	3	29
STAD	Positive regulation of double-strand break repair →	+0.050	+0.527	<.001	<.001	3	29
STAD	Epigenetic regulation of gene expression →	+0.062	+0.491	<.001	<.001	3	29
STAD	Nuclear envelope organization →	+0.062	+0.443	<.001	<.001	3	28
STAD	Vacuolar transport →	+0.066	+0.557	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,090 associations by consensus.

Positive regulation of DNA metabolic process by CDC42-IT1 expression — STAD

Explore this box plot interactively →