CDC42-IT1

Across TCGA pan-cancer cohorts, CDC42-IT1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of CDC42-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where CDC42-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CDC42-IT1 is over-expressed in tumor, although a few such as UCEC and LUAD show the opposite, repressed pattern.

BLCA, COAD, and UCEC are the cancer types where CDC42-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CDC42-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.362	.002	6	view →
COAD	All	All	+0.187	.001	6	view →
UCEC	All	II,III,IV	−0.336	.019	4	view →
STAD	Male	All	+0.421	.004	3	view →
LUAD	Female	II,III,IV	−0.256	.039	1	view →
KIRC	Female	IV	−0.226	.028	1	view →
CHOL	All	All	+0.221	.013	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

CDC42-IT1–BLCA

Open the BLCA breakdown →