CDC25B

Across TCGA patient cohorts, CDC25B protein abundance is significantly associated with the RNA expression of many other genes, with 1,853 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CDC25B-associated genes across cancer lineages are GRK4, VWA5A, and TMCO2. Each is linked with CDC25B in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC25B-to-partner and partner-to-CDC25B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDC25B versus GRK4 in BRCA, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC25B→partner) and Y-score (partner→CDC25B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GRK4 →	-0.678	-0.648	<.001	.003	3	2
HNSC	VWA5A →	-0.896	-0.753	.006	.001	3	1
HNSC	TMCO2 →	-0.286	-0.704	.001	.004	3	1
HNSC	RNU6-800P →	-0.932	-0.547	.001	.002	3	1
HNSC	SH3D21 →	+0.918	+0.693	<.001	.001	3	1
HNSC	AK4P5 →	-0.160	-0.744	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,853 associations by consensus.

CDC25B vs GRK4 — BRCA

Explore this scatter interactively →