CDC25B

Across TCGA cell cohorts, CDC25B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CDC25B-associated genes across cancer lineages are FAM47A, C7orf77, and POTED. Each is linked with CDC25B in more than 1 cancer types. Because this analysis shows association rather than direction, both CDC25B-to-partner and partner-to-CDC25B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47A grouped by CDC25B-low versus CDC25B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDC25B→partner) and Y-score (partner→CDC25B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FAM47A →	+0.026	+4.867	<.001	.009	3	2
LUNG_NSCLC_LUSC	C7orf77 →	+0.036	+4.643	<.001	.008	3	1
BLOOD_Lymphoma	POTED →	+1.395	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR5P2 →	+0.021	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ZNF728 →	+1.130	+4.867	<.001	.009	3	1
BLOOD_Leukemia	AWAT2 →	+0.015	+4.705	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

FAM47A by CDC25B expression — BLOOD_Lymphoma

Explore this box plot interactively →