CDA

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CDA RNA expression is significantly associated with the RNA expression of many other genes, with 15,695 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible CDA-associated genes across cancer lineages are CEBPB, PROCR, and RRAS. Each is linked with CDA in more than 25 cancer types. Because this analysis shows association rather than direction, both CDA-to-partner and partner-to-CDA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CDA versus CEBPB in LAML, with a Pearson correlation of 0.66.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDA→partner) and Y-score (partner→CDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LAMLCEBPB →+1.439+2.623<.001<.001326
SARCPROCR →+1.340+1.371<.001<.001325
DLBCRRAS →+1.215+1.799<.001<.001226
LAMLS100A9 →+4.602+3.278<.001<.001324
UVMCAVIN3 →+1.922+0.523<.001.004224
PAADPLK3 →+0.895+1.763<.001<.001323
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,695 associations by consensus.

CDA vs CEBPB — LAML

Per-sample scatter of CDA vs CEBPB in LAML (Pearson r = 0.66).

Explore this scatter interactively →

Exploration