CDA

Across TCGA cell cohorts, CDA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,867 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CDA-associated GO terms across cancer lineages are Mitochondrion to lysosome vesicle-mediated transport, Mitochondrion-derived vesicle mediated transport, and Regulation of proteolysis. Each is linked with CDA in more than 14 cancer types. Because this analysis shows association rather than direction, both CDA-to-partner and partner-to-CDA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrion to lysosome vesicle-mediated transport grouped by CDA-low versus CDA-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CDA→partner) and Y-score (partner→CDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Mitochondrion to lysosome vesicle-mediated transport →	+0.419	+4.467	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Mitochondrion-derived vesicle mediated transport →	+0.419	+4.467	<.001	<.001	3	15
STOMACH	Regulation of proteolysis →	+0.108	+2.705	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of mitochondrial fission →	+0.881	+3.218	<.001	<.001	3	13
LIVER	Positive regulation of mitochondrial electron transport, NADH to ubiquinone →	+0.206	+3.774	<.001	<.001	3	13
LIVER	Regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway →	+0.197	+3.774	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,867 associations by consensus.

Mitochondrion to lysosome vesicle-mediated transport by CDA expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →