CD300A

Across TCGA patient cohorts, CD300A mutation is significantly associated with the RNA expression of many other genes, with 534 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD300A-associated genes across cancer lineages are TSPY15P, FAM247B, and LRRC20. Each is linked with CD300A in more than 1 cancer types. Because this analysis shows association rather than direction, both CD300A-to-partner and partner-to-CD300A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY15P grouped by CD300A-low versus CD300A-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD300A→partner) and Y-score (partner→CD300A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TSPY15P →	+0.049	+7.731	<.001	.009	3	2
SKCM	FAM247B →	+0.078	+2.256	.006	.003	3	2
SKCM	LRRC20 →	+0.674	+2.816	.001	.001	3	2
SKCM	ERFE →	+0.755	+2.826	.001	.001	3	2
SKCM	RPL23AP82 →	+0.513	+3.384	.001	.004	3	2
SKCM	TSPY8 →	+0.127	+2.884	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 534 associations by consensus.

TSPY15P by CD300A expression — BRCA

Explore this box plot interactively →