CD300A

Across TCGA pan-cancer cohorts, CD300A RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated CD300A data layer compared with 2 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher CD300A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CD300A expression acts as an unfavorable survival marker, although some lineages such as SKCM and HNSC show a favorable association.

UVM, SKCM, and ACC are the cancer types where CD300A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.388	0.795	<.001	96	view →
SKCM	OS	Median	All	0.409	0.262	<.001	64	view →
ACC	OS	Median	III,IV	0.234	0.714	.002	40	view →
LGG	DFS	Median	All	0.332	0.473	<.001	39	view →
HNSC	DFS	Tertile	III,IV	0.665	0.466	.001	37	view →
LAML	DFS	Tertile	All	0.255	0.617	<.001	36	view →
LUSC	OS	Quartile	II,III,IV	0.502	0.714	.004	34	view →
UCEC	DFS	Quartile	III,IV	0.747	0.405	.012	28	view →
STAD	OS	Median	III,IV	0.317	0.669	.001	23	view →
CESC	DFS	Quartile	II,III,IV	0.909	0.686	.006	14	view →
KIRC	DFS	Tertile	IV	0.386	0.628	.014	14	view →
KIRP	DFS	Tertile	All	0.564	0.867	.029	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

CD300A–UVM (OS)

Open the UVM breakdown →