Across TCGA patient cohorts, CD27-AS1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CD27-AS1-associated genes across cancer lineages are RN7SL275P, NT5C1B-RDH14, and TRAV37. Each is linked with CD27-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD27-AS1-to-partner and partner-to-CD27-AS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD27-AS1→partner) and Y-score (partner→CD27-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL275P →	+0.267	+5.081	.001	.008	3	1
UCEC	NT5C1B-RDH14 →	+0.077	+5.852	<.001	.003	3	1
UCEC	TRAV37 →	+0.270	+5.420	<.001	.005	3	1
HNSC	RNU6-1325P →	+0.338	+7.954	<.001	.008	3	1
HNSC	USP9YP22 →	+0.089	+7.954	<.001	.008	3	1
HNSC	MIR4704 →	+0.438	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

CD27-AS1 survival (RNA) · tumor vs normal (RNA) · all CD27-AS1 data types