CD200

Across TCGA patient cohorts, CD200 protein abundance is significantly associated with the RNA expression of many other genes, with 12,460 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CD200-associated genes across cancer lineages are TCF4, RASGRF2, and LHFPL6. Each is linked with CD200 in more than 6 cancer types. Because this analysis shows association rather than direction, both CD200-to-partner and partner-to-CD200 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CD200 versus TCF4 in CCRCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD200→partner) and Y-score (partner→CD200) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TCF4 →	+0.767	+0.431	<.001	<.001	3	7
GBM	RASGRF2 →	+0.704	+0.524	<.001	<.001	3	6
CCRCC	LHFPL6 →	+0.929	+0.425	<.001	<.001	3	6
GBM	GNG2 →	+0.733	+0.465	<.001	.005	3	6
CCRCC	CNRIP1 →	+0.733	+0.532	<.001	<.001	3	6
LSCC	MEF2C →	+0.679	+0.471	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,460 associations by consensus.

CD200 vs TCF4 — CCRCC

Explore this scatter interactively →