CD163L1

Across TCGA cell cohorts, CD163L1 mutation is significantly associated with the RNA expression of many other genes, with 486 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CD163L1-associated genes across cancer lineages are FUT10, ELP2, and MDH1. Each is linked with CD163L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CD163L1-to-partner and partner-to-CD163L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FUT10 grouped by CD163L1-low versus CD163L1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CD163L1→partner) and Y-score (partner→CD163L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	FUT10 →	+0.497	+2.495	.009	.006	3	2
LARGE_INTESTINE	ELP2 →	+0.576	+2.628	.004	.002	3	2
LARGE_INTESTINE	MDH1 →	+0.520	+2.628	.003	.002	3	2
LARGE_INTESTINE	SPIN3 →	-1.498	-3.321	<.001	.003	3	2
LARGE_INTESTINE	ZNF630 →	-0.680	-3.459	<.001	.001	3	2
LARGE_INTESTINE	ZNF280B →	+0.727	+3.321	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 486 associations by consensus.

FUT10 by CD163L1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →