CD163L1

Across TCGA pan-cancer cohorts, CD163L1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CD163L1 data layer compared with 10 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher CD163L1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CD163L1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and HNSC show a favorable association.

UVM, BRCA, and KIRP are the cancer types where CD163L1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.326	0.713	<.001	105	view →
BRCA	DFS	Median	All	0.438	0.601	<.001	93	view →
KIRP	DFS	Median	II,III,IV	0.309	0.678	<.001	60	view →
LUSC	OS	Median	All	0.602	0.821	<.001	32	view →
UCS	OS	Tertile	III,IV	0.252	0.597	.011	28	view →
CHOL	DFS	Tertile	All	0.884	0.139	.001	24	view →
HNSC	DFS	Quartile	III,IV	0.562	0.330	.006	22	view →
SCLC	DFS	Median	All	0.601	0.375	.009	22	view →
DLBC	DFS	Tertile	II,III,IV	0.333	1.000	.006	20	view →
ACC	OS	Tertile	IV	0.353	0.927	.024	15	view →
READ	DFS	Quartile	III,IV	0.505	0.896	.009	9	view →
STAD	OS	Tertile	IV	0.682	0.221	.019	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CD163L1–UVM (OS)

Open the UVM breakdown →