Across TCGA patient cohorts, CCT8L2 mutation is significantly associated with the RNA expression of many other genes, with 5,110 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCT8L2-associated genes across cancer lineages are TRAIP, WDR41, and USP39. Each is linked with CCT8L2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCT8L2-to-partner and partner-to-CCT8L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCT8L2→partner) and Y-score (partner→CCT8L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TRAIP →	+0.310	+1.816	.003	.006	3	5
COAD	WDR41 →	+0.372	+3.272	.005	.008	3	4
SKCM	USP39 →	+0.257	+1.700	.001	.005	3	4
SKCM	OXSR1 →	+0.412	+1.749	<.001	.003	3	4
UCEC	ZWILCH →	+0.550	+2.681	<.001	<.001	3	4
UCEC	UTP11 →	+0.371	+2.145	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,110 associations by consensus.

Exploration

CCT8L2 survival (RNA) · tumor vs normal (RNA) · all CCT8L2 data types