Across TCGA patient cohorts, CCSER1 mutation is significantly associated with the RNA expression of many other genes, with 5,659 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCSER1-associated genes across cancer lineages are CRYBB2P1, MLX, and DHDDS. Each is linked with CCSER1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCSER1-to-partner and partner-to-CCSER1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCSER1→partner) and Y-score (partner→CCSER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CRYBB2P1 →	+0.483	+1.928	<.001	<.001	3	3
UCEC	MLX →	+0.526	+2.146	<.001	<.001	3	3
UCEC	DHDDS →	+0.414	+1.917	<.001	<.001	3	3
COAD	ERP27 →	-1.135	-3.584	.007	.002	3	3
SKCM	TBCD →	+0.396	+3.038	.001	<.001	3	3
UCEC	NT5C3B →	+0.436	+4.153	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,659 associations by consensus.

Exploration

CCSER1 survival (RNA) · tumor vs normal (RNA) · all CCSER1 data types