Across TCGA cell cohorts, CCSER1 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCSER1-associated genes across cancer lineages are ACER1, SERPINA7, and CXorf51A. Each is linked with CCSER1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCSER1-to-partner and partner-to-CCSER1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCSER1→partner) and Y-score (partner→CCSER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACER1 →	+0.069	+2.086	.001	.009	3	2
SOFT_TISSUE	SERPINA7 →	+0.012	+4.930	<.001	.008	3	1
SKIN	CXorf51A →	+0.494	+4.510	<.001	.001	3	1
LUNG_SCLC	OR1L6 →	+0.049	+5.029	<.001	.006	3	1
LUNG_SCLC	OR1L1 →	+0.052	+5.029	<.001	.006	3	1
BLOOD_Lymphoma	OR13C9 →	+0.024	+4.643	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

Exploration

CCSER1 survival (RNA) · tumor vs normal (RNA) · all CCSER1 data types