CCNO

Across TCGA patient cohorts, CCNO mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNO-associated genes across cancer lineages are RN7SL50P, RNU6-147P, and MIR100. Each is linked with CCNO in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNO-to-partner and partner-to-CCNO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL50P grouped by CCNO-low versus CCNO-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNO→partner) and Y-score (partner→CCNO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL50P →	+0.231	+5.038	<.001	.009	3	2
UCEC	RNU6-147P →	+0.272	+3.329	.003	.005	3	2
UCEC	MIR100 →	+0.206	+4.245	<.001	.006	3	2
SKCM	RN7SKP171 →	+0.149	+7.816	<.001	.008	3	2
UCEC	RN7SL261P →	+0.202	+3.399	<.001	.005	3	1
LIHC	RNU7-181P →	+0.824	+5.268	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

RN7SL50P by CCNO expression — BLCA

Explore this box plot interactively →