CCNO

Across TCGA pan-cancer cohorts, CCNO RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CCNO data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CCNO RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CCNO expression acts as an unfavorable survival marker, although some lineages such as BLCA and STAD show a favorable association.

KIRC, UVM, and BLCA are the cancer types where CCNO RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.561	0.692	<.001	144	view →
UVM	OS	Median	All	0.428	0.750	<.001	103	view →
BLCA	OS	Tertile	All	0.807	0.627	<.001	82	view →
ACC	OS	Median	All	0.426	0.804	<.001	72	view →
STAD	OS	Median	III,IV	0.608	0.419	.006	71	view →
CESC	OS	Tertile	IV	0.693	0.116	.012	42	view →
UCEC	OS	Median	All	0.773	0.580	.003	36	view →
UCS	DFS	Tertile	II,III,IV	0.256	0.699	.002	26	view →
LGG	OS	Median	All	0.754	0.865	<.001	21	view →
ESCA	OS	Quartile	All	0.406	1.000	.024	16	view →
HNSC	OS	Quartile	All	0.541	0.820	.005	13	view →
SKCM	DFS	Tertile	IV	0.263	0.773	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CCNO–KIRC (OS)

Open the KIRC breakdown →