CCNL1

Across TCGA patient cohorts, CCNL1 mutation is significantly associated with the RNA expression of many other genes, with 4,343 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNL1-associated genes across cancer lineages are RN7SL97P, TXNL4AP1, and UBBP3. Each is linked with CCNL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNL1-to-partner and partner-to-CCNL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL97P grouped by CCNL1-low versus CCNL1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNL1→partner) and Y-score (partner→CCNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL97P →	+0.123	+4.559	<.001	.006	3	2
COAD	TXNL4AP1 →	+0.153	+2.781	.002	.007	3	2
COAD	UBBP3 →	+0.501	+2.775	.001	.003	3	2
COAD	RPSAP35 →	+0.048	+5.153	<.001	.001	3	2
COAD	CORT →	+0.450	+3.223	<.001	.009	3	2
COAD	RN7SL83P →	+0.242	+4.169	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,343 associations by consensus.

RN7SL97P by CCNL1 expression — CESC

Explore this box plot interactively →