CCNK

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCNK protein abundance is significantly associated with the RNA expression of many other genes, with 18,176 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCNK-associated genes across cancer lineages are TMEM97, RECQL4, and AURKA. Each is linked with CCNK in more than 7 cancer types. Because this analysis shows association rather than direction, both CCNK-to-partner and partner-to-CCNK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNK versus TMEM97 in LSCC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNK→partner) and Y-score (partner→CCNK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTMEM97 →+1.082+0.229<.001<.00138
HNSCRECQL4 →+0.832+0.156<.001<.00137
UCECAURKA →+1.234+0.185<.001<.00137
UCECMYBL2 →+1.331+0.239<.001<.00136
HNSCAHCY →+0.892+0.143.001.00336
PDACRASGRF2 →-0.729-0.210<.001.00436
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,176 associations by consensus.

CCNK vs TMEM97 — LSCC

Per-sample scatter of CCNK vs TMEM97 in LSCC (Pearson r = 0.64).

Explore this scatter interactively →

Exploration