CCNF

Across TCGA patient cohorts, CCNF mutation is significantly associated with the RNA expression of many other genes, with 1,861 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNF-associated genes across cancer lineages are OR7E148P, FUZ, and UFM1. Each is linked with CCNF in more than 3 cancer types. Because this analysis shows association rather than direction, both CCNF-to-partner and partner-to-CCNF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E148P grouped by CCNF-low versus CCNF-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNF→partner) and Y-score (partner→CCNF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR7E148P →	+0.051	+4.234	.002	.008	3	4
UCEC	FUZ →	-0.611	-1.989	.004	.003	3	3
UCEC	UFM1 →	+0.479	+1.931	.003	.009	3	3
STAD	EXOSC9 →	+0.570	+3.338	<.001	.005	2	4
STAD	TPPP3 →	-1.596	-3.321	.001	.009	3	3
STAD	ZNF121 →	+0.577	+3.182	.004	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,861 associations by consensus.

OR7E148P by CCNF expression — CESC

Explore this box plot interactively →