CCND3

Across TCGA patient cohorts, CCND3 mutation is significantly associated with the RNA expression of many other genes, with 644 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCND3-associated genes across cancer lineages are SLC7A4, LCE6A, and TAPBPL. Each is linked with CCND3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCND3-to-partner and partner-to-CCND3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC7A4 grouped by CCND3-low versus CCND3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND3→partner) and Y-score (partner→CCND3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC7A4 →	-1.206	-2.668	.001	.006	3	2
LUAD	LCE6A →	+0.081	+6.584	<.001	.001	3	2
UCEC	TAPBPL →	-0.864	-2.700	<.001	.006	3	2
UCEC	SNORD3C →	+0.017	+4.035	<.001	.006	3	2
SKCM	RNU6-1211P →	+0.283	+7.816	<.001	.008	3	2
BLCA	BUD31P1 →	+0.087	+3.870	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 644 associations by consensus.

SLC7A4 by CCND3 expression — UCEC

Explore this box plot interactively →