CCND2

Across TCGA patient cohorts, CCND2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,277 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCND2-associated proteins across cancer lineages are CCND2_T280, SEPTIN7, and HAAO. Each is linked with CCND2 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCND2-to-partner and partner-to-CCND2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCND2 versus CCND2_T280 in LSCC, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND2→partner) and Y-score (partner→CCND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CCND2_T280 →	+0.759	+1.797	<.001	<.001	3	7
PDAC	SEPTIN7 →	+0.293	+0.487	<.001	<.001	3	7
UCEC	HAAO →	+0.492	+0.854	<.001	<.001	3	6
UCEC	SORBS3 →	+0.481	+0.777	<.001	<.001	3	6
CCRCC	SYNPO2 →	+0.767	+0.603	.001	.002	3	6
BRCA	SYNPO2_S729 →	+0.824	+0.851	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,277 associations by consensus.

CCND2 vs CCND2_T280 — LSCC

Explore this scatter interactively →