CCNA1

Across TCGA cell cohorts, CCNA1 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCNA1-associated genes across cancer lineages are KRTAP5-4, OR6N1, and NPVF. Each is linked with CCNA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNA1-to-partner and partner-to-CCNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP5-4 grouped by CCNA1-low versus CCNA1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNA1→partner) and Y-score (partner→CCNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	KRTAP5-4 →	+0.101	+4.977	<.001	.007	3	1
BLOOD_Lymphoma	OR6N1 →	+0.349	+4.867	<.001	.009	3	1
LUNG_NSCLC_LUAD	NPVF →	+0.011	+4.078	.002	.009	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.013	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR4D5 →	+0.011	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	SYCP1 →	+0.062	+3.719	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

KRTAP5-4 by CCNA1 expression — SKIN

Explore this box plot interactively →