CCN5

Across TCGA cell cohorts, CCN5 mutation is significantly associated with the mutation status of many other genes, with 1,051 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCN5-associated genes across cancer lineages are OR51I2, NXF1, and NOTUM. Each is linked with CCN5 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCN5-to-partner and partner-to-CCN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51I2 grouped by CCN5-low versus CCN5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN5→partner) and Y-score (partner→CCN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR51I2 →	+4.309	+4.560	.007	.007	1	4
SKIN	NXF1 →	+5.824	+5.824	.002	.002	1	3
SKIN	NOTUM →	+4.824	+5.392	.004	.004	1	3
LARGE_INTESTINE	ZNF394 →	+4.523	+5.087	.006	.006	1	3
BLOOD_Leukemia	SMAP1 →	+4.894	+4.894	.004	.004	1	3
BLOOD_Leukemia	NMBR →	+4.894	+4.894	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,051 associations by consensus.

OR51I2 by CCN5 expression — BLOOD_Leukemia

Explore this box plot interactively →