CCL8

Across TCGA patient cohorts, CCL8 protein abundance is significantly associated with the RNA expression of many other genes, with 1,728 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CCL8-associated genes across cancer lineages are EXOSC3, MIR4661, and PELO. Each is linked with CCL8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL8-to-partner and partner-to-CCL8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCL8 versus EXOSC3 in HNSC, with a Pearson correlation of -0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL8→partner) and Y-score (partner→CCL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EXOSC3 →	-0.800	-0.562	<.001	.001	3	2
HNSC	MIR4661 →	+1.347	+0.498	.009	.002	3	2
LUAD	PELO →	+0.766	+0.839	.001	.006	3	2
LUAD	USP38 →	+0.578	+0.756	.002	.001	3	2
LUAD	TANGO2 →	+0.508	+0.756	.005	.001	3	2
CCRCC	TRAV30 →	+1.910	+0.461	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,728 associations by consensus.

CCL8 vs EXOSC3 — HNSC

Explore this scatter interactively →