CCL7

Across TCGA patient cohorts, CCL7 mutation is significantly associated with the RNA expression of many other genes, with 1,606 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL7-associated genes across cancer lineages are RN7SL248P, GTSE1-DT, and RN7SL104P. Each is linked with CCL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL7-to-partner and partner-to-CCL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CCL7-low versus CCL7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL7→partner) and Y-score (partner→CCL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.062	+3.219	<.001	.004	3	2
UCEC	GTSE1-DT →	+0.545	+2.986	<.001	<.001	3	2
LUAD	RN7SL104P →	+0.071	+4.786	<.001	.003	3	2
UCEC	GLRX5 →	+0.415	+2.839	.002	.001	3	2
UCEC	RPL23AP82 →	+0.492	+2.606	<.001	.005	3	2
UCEC	WDHD1 →	+0.693	+2.021	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,606 associations by consensus.

RN7SL248P by CCL7 expression — UCEC

Explore this box plot interactively →