CCL23

Across TCGA patient cohorts, CCL23 mutation is significantly associated with the RNA expression of many other genes, with 78 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CCL23-associated genes across cancer lineages are TUBB4BP3, LINC02414, and RNU6-391P. Each is linked with CCL23 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL23-to-partner and partner-to-CCL23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TUBB4BP3 grouped by CCL23-low versus CCL23-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL23→partner) and Y-score (partner→CCL23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TUBB4BP3 →	+0.327	+3.298	<.001	.004	3	2
LUAD	LINC02414 →	+0.308	+4.303	<.001	.009	3	2
BRCA	RNU6-391P →	+0.331	+7.731	<.001	.009	3	1
BRCA	RNY1P7 →	+0.318	+8.055	<.001	.007	3	1
BRCA	CPLX3 →	+0.154	+8.055	<.001	.007	3	1
BRCA	LINC00353 →	+0.059	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 78 associations by consensus.

TUBB4BP3 by CCL23 expression — UCEC

Explore this box plot interactively →