CCL21

Across TCGA patient cohorts, CCL21 protein abundance is significantly associated with the RNA expression of many other genes, with 8,034 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CCL21-associated genes across cancer lineages are MMRN1, SGCA, and MYCT1. Each is linked with CCL21 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCL21-to-partner and partner-to-CCL21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCL21 versus MMRN1 in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL21→partner) and Y-score (partner→CCL21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MMRN1 →	+1.069	+0.861	<.001	.001	3	7
HNSC	SGCA →	+0.902	+0.618	<.001	<.001	3	6
UCEC	MYCT1 →	+1.076	+1.313	<.001	<.001	3	6
UCEC	RHOJ →	+0.993	+1.125	<.001	<.001	3	6
COAD	LYVE1 →	+1.144	+0.710	.002	.001	3	6
UCEC	PGM5 →	+1.945	+1.035	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,034 associations by consensus.

CCL21 vs MMRN1 — UCEC

Explore this scatter interactively →