CCL20

Across TCGA patient cohorts, CCL20 protein abundance is significantly associated with the RNA expression of many other genes, with 2,650 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL20-associated genes across cancer lineages are CXCL8, PI3, and USP6NL. Each is linked with CCL20 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCL20-to-partner and partner-to-CCL20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCL20 versus CXCL8 in GBM, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL20→partner) and Y-score (partner→CCL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CXCL8 →	+3.164	+1.884	<.001	.001	3	4
GBM	PI3 →	+3.979	+1.782	<.001	.002	3	3
UCEC	USP6NL →	-0.524	-0.894	.002	<.001	3	3
GBM	SAA1 →	+3.583	+1.527	<.001	.002	3	3
LSCC	MYEF2 →	-0.957	-1.257	<.001	.001	3	2
UCEC	WLS →	-0.864	-1.152	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,650 associations by consensus.

CCL20 vs CXCL8 — GBM

Explore this scatter interactively →