CCL18

Across TCGA patient cohorts, CCL18 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL18-associated genes across cancer lineages are MIR8054, RNU1-17P, and RNU4-52P. Each is linked with CCL18 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL18-to-partner and partner-to-CCL18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8054 grouped by CCL18-low versus CCL18-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL18→partner) and Y-score (partner→CCL18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR8054 →	+0.262	+7.816	<.001	.008	3	1
UCEC	RNU1-17P →	+0.299	+3.198	<.001	.009	3	1
UCEC	RNU4-52P →	+0.698	+3.663	.006	.005	3	1
UCEC	RNU6-1340P →	+0.359	+3.396	.002	.006	3	1
UCEC	MT-TA →	+0.382	+3.747	<.001	.003	3	1
UCEC	TRAV18 →	+0.246	+3.004	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

MIR8054 by CCL18 expression — SKCM

Explore this box plot interactively →