CCL15-CCL14

Across TCGA patient cohorts, CCL15-CCL14 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,983 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible CCL15-CCL14-associated GO terms across cancer lineages are Leukotriene catabolic process, Regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation, and Digestion. Each is linked with CCL15-CCL14 in more than 10 cancer types. Because this analysis shows association rather than direction, both CCL15-CCL14-to-partner and partner-to-CCL15-CCL14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leukotriene catabolic process grouped by CCL15-CCL14-low versus CCL15-CCL14-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL15-CCL14→partner) and Y-score (partner→CCL15-CCL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Leukotriene catabolic process →	+0.395	+0.427	<.001	<.001	3	11
ESCA	Regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation →	+0.100	+0.555	<.001	<.001	3	11
ESCA	Digestion →	+0.084	+0.777	<.001	<.001	3	11
ESCA	Positive regulation of dendritic cell differentiation →	+0.091	+0.620	<.001	<.001	3	10
ESCA	Calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules →	+0.161	+0.852	<.001	<.001	3	10
ESCA	Regulation of granulocyte differentiation →	+0.066	+0.589	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,983 associations by consensus.

Leukotriene catabolic process by CCL15-CCL14 expression — ESCA

Explore this box plot interactively →