CCL15-CCL14

Across TCGA pan-cancer cohorts, CCL15-CCL14 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CCL15-CCL14 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher CCL15-CCL14 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CCL15-CCL14 expression acts as an unfavorable survival marker, although some lineages such as KIRP and BLCA show a favorable association.

KIRP, BLCA, and KICH are the cancer types where CCL15-CCL14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	IV	0.593	0.039	.008	52	view →
BLCA	OS	Median	All	0.699	0.527	<.001	50	view →
KICH	DFS	Quartile	III,IV	0.047	0.811	<.001	48	view →
OV	DFS	Tertile	All	0.631	0.519	.016	36	view →
UCEC	DFS	Tertile	IV	0.208	0.576	.012	36	view →
LGG	OS	Tertile	All	0.770	0.923	<.001	30	view →
ACC	DFS	Tertile	III,IV	0.039	0.381	.008	27	view →
READ	DFS	Quartile	All	0.887	0.717	.007	24	view →
KIRC	DFS	Quartile	IV	0.553	0.268	.006	17	view →
ESCA	OS	Median	All	0.617	1.000	.009	15	view →
DLBC	DFS	Tertile	All	1.000	0.731	.015	11	view →
GBM	OS	Tertile	All	0.274	0.431	.040	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CCL15-CCL14–KIRP (DFS)

Open the KIRP breakdown →