CCL13

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCL13 mutation is significantly associated with the mutation status of many other genes, with 256 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCL13-associated genes across cancer lineages are LIPK, GORASP1, and CARS2. Each is linked with CCL13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL13-to-partner and partner-to-CCL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIPK grouped by CCL13-low versus CCL13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL13→partner) and Y-score (partner→CCL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINELIPK →+5.523+5.523.003.00312
BLOOD_LeukemiaGORASP1 →+6.321+6.321.001.00112
BLOOD_LeukemiaCARS2 →+4.321+5.285.005.00512
BLOOD_LeukemiaNPEPPS →+4.000+5.050.008.00812
BLOOD_LeukemiaARFGAP2 →+4.000+5.050.008.00812
BLOOD_LeukemiaFZD6 →+4.321+5.285.005.00512
Each partner links to its Q-omics profile. Showing the 6 strongest of 256 associations by consensus.

LIPK by CCL13 expression — LARGE_INTESTINE

Box plot of LIPK in CCL13-low vs CCL13-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration