CCER1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCER1 mutation is significantly associated with the RNA expression of many other genes, with 2,812 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCER1-associated genes across cancer lineages are RBBP8, PSMC3IP, and CABCOCO1. Each is linked with CCER1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCER1-to-partner and partner-to-CCER1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCER1→partner) and Y-score (partner→CCER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRBBP8 →+0.618+1.854.005.00533
UCECPSMC3IP →+0.526+1.765<.001<.00133
UCECCABCOCO1 →-0.992-2.297<.001.00133
SKCMWDHD1 →+0.521+2.267.006.00133
UCECPRC1 →+0.470+1.815.009.00233
UCECRNU6-879P →+0.243+1.456.008.00933
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,812 associations by consensus.

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