CCDC96

Across TCGA patient cohorts, CCDC96 mutation is significantly associated with the RNA expression of many other genes, with 1,585 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC96-associated genes across cancer lineages are LSM11, SEC13, and BOLA3. Each is linked with CCDC96 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC96-to-partner and partner-to-CCDC96 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LSM11 grouped by CCDC96-low versus CCDC96-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC96→partner) and Y-score (partner→CCDC96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM11 →	+0.396	+3.595	.004	.001	3	2
UCEC	SEC13 →	+0.402	+3.202	.002	.009	3	2
UCEC	BOLA3 →	+0.456	+3.042	.002	<.001	3	2
UCEC	MON1A →	+0.427	+3.470	<.001	.002	3	2
UCEC	UQCRQ →	+0.426	+3.343	.002	.005	3	2
UCEC	PHAX →	+0.508	+3.625	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,585 associations by consensus.

LSM11 by CCDC96 expression — UCEC

Explore this box plot interactively →