CCDC86

Across TCGA patient cohorts, CCDC86 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,641 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC86-associated proteins across cancer lineages are FEN1, WDR75, and SMC2. Each is linked with CCDC86 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCDC86-to-partner and partner-to-CCDC86 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC86 versus FEN1 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC86→partner) and Y-score (partner→CCDC86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FEN1 →	+0.481	+0.421	.003	.003	3	8
LSCC	WDR75 →	+0.392	+0.746	<.001	<.001	3	7
UCEC	SMC2 →	+0.568	+0.679	<.001	.001	3	7
BRCA	SMC4 →	+0.547	+0.518	<.001	.002	3	7
PDAC	CCDC86_S18 →	+0.557	+0.368	<.001	<.001	3	7
LSCC	PUS7 →	+0.465	+0.697	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,641 associations by consensus.

CCDC86 vs FEN1 — OV

Explore this scatter interactively →