CCDC86

Across TCGA pan-cancer cohorts, CCDC86 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CCDC86’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CCDC86 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC86 is over-expressed in tumor.

KIRC, COAD, and KIRP are the cancer types where CCDC86 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC86 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.785	<.001	12	view →
COAD	Female	II,III,IV	+1.607	<.001	11	view →
KIRP	All	IV	+1.435	<.001	11	view →
HNSC	Male	III,IV	+1.347	<.001	11	view →
STAD	Male	II,III,IV	+1.699	<.001	9	view →
LIHC	Male	II,III,IV	+1.658	<.001	9	view →
LUAD	Female	III,IV	+1.125	<.001	9	view →
LUSC	Male	III,IV	+2.092	<.001	8	view →
BLCA	Male	All	+1.008	<.001	8	view →
CHOL	Male	All	+2.261	<.001	5	view →
READ	All	All	+0.942	.005	4	view →
PAAD	Female	All	+0.629	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CCDC86–KIRC

Open the KIRC breakdown →