CCDC86

Across TCGA patient cohorts, CCDC86 protein abundance is significantly associated with the RNA expression of many other genes, with 12,674 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC86-associated genes across cancer lineages are NME1, EIF3E, and LMOD1. Each is linked with CCDC86 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC86-to-partner and partner-to-CCDC86 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC86 versus NME1 in LUAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC86→partner) and Y-score (partner→CCDC86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NME1 →	+0.711	+0.258	<.001	<.001	3	7
OV	EIF3E →	+0.775	+0.402	<.001	.001	3	6
OV	LMOD1 →	-1.138	-0.299	<.001	<.001	3	6
OV	CMAHP →	-0.720	-0.255	.001	.004	3	6
LUAD	NHP2 →	+0.473	+0.178	<.001	.002	3	6
HNSC	WDR74 →	+0.487	+0.301	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,674 associations by consensus.

CCDC86 vs NME1 — LUAD

Explore this scatter interactively →