CCDC83

Across TCGA patient cohorts, CCDC83 mutation is significantly associated with the RNA expression of many other genes, with 2,374 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC83-associated genes across cancer lineages are KRTAP1-4, ACTG1P25, and ALKBH6. Each is linked with CCDC83 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC83-to-partner and partner-to-CCDC83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP1-4 grouped by CCDC83-low versus CCDC83-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC83→partner) and Y-score (partner→CCDC83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	KRTAP1-4 →	+0.238	+7.164	<.001	<.001	3	2
SKCM	ACTG1P25 →	+0.353	+2.328	.001	.003	3	2
SKCM	ALKBH6 →	+0.286	+2.613	.006	.005	3	2
SKCM	PDXP →	+0.689	+3.044	<.001	<.001	3	2
SKCM	MTFP1 →	+0.660	+4.106	<.001	<.001	3	2
UCEC	CDK11B →	+0.420	+3.032	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,374 associations by consensus.

KRTAP1-4 by CCDC83 expression — CESC

Explore this box plot interactively →