CCDC83

Across TCGA cell cohorts, CCDC83 RNA expression is significantly associated with the go_rna of many other GO terms, with 317 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CCDC83-associated GO terms across cancer lineages are Megakaryocyte differentiation, Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway, and Positive regulation of endoplasmic reticulum unfolded protein response. Each is linked with CCDC83 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC83-to-partner and partner-to-CCDC83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Megakaryocyte differentiation grouped by CCDC83-low versus CCDC83-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC83→partner) and Y-score (partner→CCDC83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Megakaryocyte differentiation →	-0.077	-0.091	<.001	.004	3	3
LARGE_INTESTINE	Nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway →	-0.049	-0.097	.001	<.001	3	3
BREAST	Positive regulation of endoplasmic reticulum unfolded protein response →	+0.076	+0.438	.001	.009	3	3
BREAST	Negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.056	+0.323	.002	<.001	3	3
BREAST	Vesicle localization →	+0.040	+0.288	<.001	.002	3	3
BREAST	Regulation of activation-induced cell death of T cells →	+0.191	+0.381	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 317 associations by consensus.

Megakaryocyte differentiation by CCDC83 expression — LARGE_INTESTINE

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