CCDC81

Across TCGA cell cohorts, CCDC81 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CCDC81-associated genes across cancer lineages are PF4, OR52N4, and SNTN. Each is linked with CCDC81 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC81-to-partner and partner-to-CCDC81 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PF4 grouped by CCDC81-low versus CCDC81-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC81→partner) and Y-score (partner→CCDC81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PF4 →	+0.044	+4.867	<.001	.009	3	2
SOFT_TISSUE	OR52N4 →	+0.079	+4.882	<.001	.001	3	1
SOFT_TISSUE	SNTN →	+0.017	+4.977	<.001	.002	3	1
SOFT_TISSUE	C9orf92 →	+0.144	+4.369	<.001	.008	3	1
SOFT_TISSUE	KRTAP2-1 →	+0.107	+4.417	<.001	.004	3	1
SOFT_TISSUE	POTEB →	+0.072	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

PF4 by CCDC81 expression — BLOOD_Lymphoma

Explore this box plot interactively →