CCDC74BP1

Across TCGA patient cohorts, CCDC74BP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,092 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CCDC74BP1-associated proteins across cancer lineages are RIC8A_T441, SEC63_T537, and AP4B1_S593. Each is linked with CCDC74BP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCDC74BP1-to-partner and partner-to-CCDC74BP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC74BP1 versus RIC8A_T441 in PDAC, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC74BP1→partner) and Y-score (partner→CCDC74BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RIC8A_T441 →	-0.921	-0.265	<.001	<.001	3	4
GBM	SEC63_T537 →	-0.917	-0.460	<.001	<.001	3	4
GBM	AP4B1_S593 →	-0.519	-0.298	<.001	<.001	3	4
LSCC	THUMPD1_S88 →	-0.842	-0.528	<.001	<.001	3	4
GBM	PHKA1_S758 →	-0.931	-0.317	<.001	.001	3	3
CCRCC	PHRF1_S814 →	-0.594	-0.341	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,092 associations by consensus.

CCDC74BP1 vs RIC8A_T441 — PDAC

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