CCDC74BP1

Across TCGA pan-cancer cohorts, CCDC74BP1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated CCDC74BP1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CCDC74BP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CCDC74BP1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and THYM show a favorable association.

ACC, ESCA, and THYM are the cancer types where CCDC74BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.374	0.825	<.001	93	view →
ESCA	OS	Quartile	II,III,IV	0.821	0.387	.003	27	view →
THYM	DFS	Median	II,III,IV	1.000	0.734	.004	19	view →
KIRC	OS	Quartile	All	0.539	0.658	.010	18	view →
UCEC	OS	Quartile	All	0.884	0.936	.006	14	view →
CESC	OS	Quartile	All	0.943	0.835	.014	8	view →
BLCA	OS	Tertile	IV	0.134	0.340	.017	6	view →
LUSC	OS	Median	III,IV	0.805	0.266	.013	4	view →
KIRP	OS	Quartile	III,IV	0.759	0.322	.024	2	view →
UCS	DFS	Quartile	All	0.675	0.416	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

CCDC74BP1–ACC (OS)

Open the ACC breakdown →